Bacteria that cause infectious diseases adopt biofilms as one of their most prevalent lifestyles.Biofilms enable bacteria to tolerate environmental stress and evade antibacterial agents.This bacterial defense mechanism has rendered the use of antibiotics ineffective for the treatment of infectious diseases.However, many highly drug-resistant microb
Background and objectives: In children, acute infection is the most common cause of visits in the primary care or emergency department.In 2002, criteria for diagnostics of pediatric sepsis were published, and then revised in 2016 as “life-threatening organ dysfunction due to a dysregulated host response to infection”.In the pathophysiol
Lung cancer is the leading cause of cancer deaths worldwide.Clinically, the treatment of non-small cell lung cancer (NSCLC) can be improved by the early detection and risk screening among population.To meet this need, here we describe the application of extensive peptide level fractionation coupled with label free quantitative proteomics for the di
Every year, numerous major events with thousands of participants Lamps take place around the world, for which extensive safety measures are taken to ensure the well-being and safety of visitors.Nevertheless, incidents that lead to injuries and deaths occur time and again.This year, Germany is looking forward to the UEFA EURO 2024, an international
A bacterial membrane protein ZipA that tethers FtsZ to the membrane is known to promote FtsZ assembly.In this study, the Telephone Antenna binding of ZipA to FtsZ was monitored using fluorescence spectroscopy.ZipA was found to bind to FtsZ with high affinities at three different (6.0, 6.8 and 8.0) pHs, albeit the binding affinity decreased with inc